resveratrol.jpg no2  Natural compound found in red wine could help overweight men build bone density

Some of these risk factors include "abdominal obesity, high levels of fats in the blood called triglycerides, elevated blood pressure, high fasting blood sugar and reduced high-density lipoprotein (HDL), or good, cholesterol levels," according to a press release by Endocrine Society.

"Our study is the first to reveal resveratrol's potential as an anti-osteoporosis drug in humans," said one of the study's authors, Marie Juul Ornstrup, MD, with Aarhus University Hospital in Aarhus, Denmark.

"Our findings suggest the compound stimulates bone-forming cells within the body," she added.

Through a randomized and double-blinded trial involving a placebo, scientists analyzed bone mineral density and signs of bone formation and resorption in overweight men 66 years of age.

For a period of 16 weeks, the participants were given either a 500-milligram dose of resveratrol, a 75-millgram dose of the compound or a placebo twice daily.

The men receiving the naturally occurring compound found in red wine reaped the most benefits, showing significant bone growth. Those who received the higher dose of resveratrol experienced a 2.6 percent increase in lumbar spine volumetric mineral density compared to the men who received the placebo.

The study's results indicate that the higher the dosage of resveratrol, the better the benefits. The men who received the 500-milligram dose of resveratrol exhibited "a 16 percent increase in levels of the bone formation marker bone alkaline phosphatase (BAP)," compared to the participants who took the placebo.

"In just four months on high-dose resveratrol, we saw significant improvements in bone mineral density at the spine and elevated levels of the bone formation marker BAP," said Ornstrup.

"These are encouraging results. Additional research is needed to assess whether these bone protective effects occur in populations at risk of osteoporosis during the course of long-term treatment."

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